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GLP-1 / Weight Loss Head-to-head comparison

Sesame Care vs MEDVi

True annual cost, labs inclusion, delivery methods, and verified reviews compared. Updated March 2026.

Our pick: MEDVi8.5/10 vs 8.3/10, higher rated
Sesame Care
Direct-to-patient marketplace — GLP-1, ED, HRT, mental health from $16/appt
8.3/10
Monthly
$16/mo
True Annual
$192/yr
Labs
✗ Extra
States
All 50
Pros
Available in all 50 states
No insurance required — transparent cash pricing
Same-day telehealth or in-person appointments
Cons
Marketplace model — quality varies by provider
Lower recurring revenue than subscription clinics
Visit Sesame Care
VS
★ Our Pick
MEDVi
$179/mo first month — top-rated GLP-1 provider
8.5/10
Monthly
$179/mo
True Annual
$3,348/yr
Labs
✗ Extra
States
All 50
Pros
Top-rated GLP-1 provider (100k+ patients)
Both sema and tirzepatide
LegitScript certified
Cons
Ongoing cost $299/mo is higher
No labs included
Visit MEDVi

Side-by-side comparison

FeatureSesame CareMEDVi
Monthly price$16/mo$179/mo
True annual cost$192/yr$3,348/yr
Labs included✗ No✗ No
Delivery optionsoral, injection, topicalinjection
Editorial score8.3/108.5/10
Trustpilot4.5★4.7★
State availabilityAll 50 statesAll 50 states

Our verdict

MEDVi (8.5/10) is our pick over Sesame Care (8.3/10) for most patients.

Sesame Care may be a better fit if you want more delivery options (oral, injection, topical). Both clinics require a prescription and blood work before starting treatment.

Visit MEDViSee all GLP-1 / Weight Loss clinics →

More GLP-1 / Weight Loss comparisons

MEDVi vs Remedy Meds
$179/mo vs $179/mo · 8.5 vs 9.5 score
MEDVi vs DirectMeds
$179/mo vs $199/mo · 8.5 vs 8.8 score
MEDVi vs CareBare
$179/mo vs $199/mo · 8.5 vs 8.7 score
MEDVi vs Enhance MD
$179/mo vs $115/mo · 8.5 vs 8.7 score
Sesame Care vs Remedy Meds
$16/mo vs $179/mo · 8.3 vs 9.5 score
Sesame Care vs DirectMeds
$16/mo vs $199/mo · 8.3 vs 8.8 score
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