Compare Peptides clinics
Every major clinic ranked by true all-in annual cost. The headline price is never the full story.
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What does Peptide Therapy actually cost in 2026?
Peptide therapy from a licensed telehealth clinic costs between $2,388 and $2,800 per year based on the providers we track — a range that reflects the fact that peptides are a specialty category requiring physician oversight, compounding pharmacy access, and injectable supplies. There is no low-cost commodity option here equivalent to generic finasteride or oral sildenafil.
The most affordable peptide therapy option is Maximus at $199/mo ($2,388/yr) with labs included and all-50-state coverage. Defy Medical at $200–$250/mo is the most comprehensive option — the widest peptide formulary and most experienced physicians — but costs up to $2,800+/yr. Marek Health charges $166+/mo but adds $450–$1,700/yr in lab costs depending on your protocol, making it the most expensive option despite the lower headline price.
Most peptide subscriptions do not include labs. Labs for peptide protocols — IGF-1 for growth hormone peptides, comprehensive metabolic panels — add $250–$700/yr to clinics that don't include them. Defy Medical and Maximus both include labs in their programs. Factor this in when comparing headline prices.
NAD+ therapy, offered by MYRNK and Defy Medical, is a distinct but related category. NAD+ infusions run $200–$400 per session at in-person IV clinics; subcutaneous NAD+ injections through telehealth are significantly more affordable. MYRNK offers both sermorelin and NAD+ through the same platform, making it convenient for patients interested in both protocols.
What's included in a Peptide Therapy subscription?
A peptide therapy subscription typically includes: an initial consultation with a physician familiar with peptide protocols, a prescription for the specific peptide compounds, the peptides from a licensed 503A/503B compounding pharmacy, injection supplies (syringes, bacteriostatic water for reconstitution), and follow-up consultations. Because all prescription peptides are injectable, intake also covers injection technique (via video or written instructions).
Peptide categories available through telehealth clinics: growth hormone secretagogues (sermorelin, ipamorelin, CJC-1295 — stimulate natural GH release from the pituitary), tissue repair peptides (BPC-157 for joint and gut healing, TB-500 for soft tissue recovery), and longevity compounds (NAD+ subcutaneous injections). TRT Nation also offers BPC-157 alongside their testosterone protocols for existing patients.
The distinction between growth hormone secretagogues and synthetic HGH matters both legally and clinically. Sermorelin, ipamorelin, and CJC-1295 are legal to prescribe and compound; they work by stimulating your pituitary to produce more of your own GH. Synthetic HGH (somatropin) is a Schedule III controlled substance with strict federal prescribing requirements. The clinics listed here use secretagogues, not synthetic HGH.
Reconstitution and storage add a small ongoing cost: bacteriostatic water and insulin syringes are inexpensive but need to be factored in. Reconstituted peptides typically store in the refrigerator for 4–8 weeks. Most clinics ship lyophilized (freeze-dried) powder with detailed reconstitution instructions.
How to compare online Peptide Therapy clinics
Verify that the clinic uses a licensed 503A or 503B compounding pharmacy. All peptides prescribed through legitimate telehealth clinics are compounded — there are no FDA-approved standalone versions of sermorelin, BPC-157, or ipamorelin as drugs. Legitimate operations are transparent about their pharmacy partners. All providers listed on ClinicLayer are verified before listing.
Match the clinic to your specific protocol goal. Defy Medical has the broadest peptide formulary — if you want a less common peptide (TB-500, PT-141, Epithalon), they're the most likely to have it. Maximus focuses on growth hormone secretagogues alongside TRT. MYRNK focuses on NAD+ and sermorelin. TRT Nation is primarily a TRT clinic that offers BPC-157 as an add-on.
Consider whether you want a dedicated peptide specialist or a broader men's health platform. If you're already on TRT and want to add peptides, Maximus or TRT Nation allow you to manage both from the same provider. If peptide optimization is your primary goal, Defy Medical and Marek Health have deeper physician expertise in peptide-specific protocols and monitoring.
Confirm lab requirements upfront. Growth hormone peptide protocols require IGF-1 monitoring to verify your GH output is responding appropriately and staying within physiological ranges. A provider that skips this step is not running a serious protocol — IGF-1 should be checked before starting and at 3-month intervals.
Frequently asked questions
How much does sermorelin therapy cost per month?
Sermorelin therapy through a telehealth clinic costs $199–$250/mo ($2,388–$3,000/yr) in 2026. MYRNK and Maximus are at the $199/mo end; Defy Medical and Marek Health are higher. Labs (IGF-1 monitoring) are required and included at Defy Medical and Maximus, but not at MYRNK — budget an additional $200–$400/yr for labs if they're not included.
Is BPC-157 legal to prescribe online?
BPC-157 exists in a regulatory gray area as of 2026. It is not FDA-approved as a standalone drug, but it can be legally prescribed by a licensed physician and compounded by a licensed 503A pharmacy for individual patients — the same legal framework used for all other compounded peptides. TRT Nation and Defy Medical both offer BPC-157 this way. The legitimacy depends entirely on the prescribing physician and their pharmacy.
What is the difference between sermorelin and HGH?
Sermorelin is a growth hormone releasing hormone (GHRH) analog — it signals your pituitary gland to produce and release more of your own natural growth hormone. Synthetic HGH (somatropin) directly replaces GH. Sermorelin is legal to prescribe and compound; synthetic HGH is a Schedule III controlled substance with strict prescribing requirements. Sermorelin produces smaller, more physiological GH pulses and is generally considered safer for long-term use than exogenous HGH.
Do I need bloodwork to start peptide therapy?
Yes — any legitimate peptide clinic will require baseline labs before prescribing. For growth hormone peptides (sermorelin, ipamorelin), the key marker is IGF-1, which reflects your average GH output. A complete metabolic panel and CBC are also standard. Defy Medical and Maximus include these labs in the subscription. MYRNK and Marek Health require labs but price them separately — add $200–$700/yr to those costs depending on the panel.