GLP-1 / Weight Loss › Head-to-head comparison
DirectMeds vs Zealthy
True annual cost, labs inclusion, delivery methods, and verified reviews compared. Updated March 2026.
★
Our pick: DirectMeds — 8.8/10 vs 8.3/10, higher rated
★ Our Pick
DirectMeds
Compounded GLP-1 from $199/mo — semaglutide and tirzepatide, labs optional
8.8/10
Monthly
$199/mo
True Annual
$2,388/yr
Labs
✗ Extra
States
All 50
Pros
✓Fast approval process — under 24 hours
✓Compounded sema and tirzepatide available
✓Free shipping on all orders
Cons
✗Labs not included
✗Newer provider
VS
Zealthy
Weight loss programs from $99/mo — easy online approval
8.3/10
Monthly
$99/mo
True Annual
$1,188/yr
Labs
✗ Extra
States
All 50
Pros
✓Low monthly price
✓Multiple program tiers
✓Approved affiliate
Cons
✗Newer brand
✗Coaching not always included
Side-by-side comparison
| Feature | DirectMeds | Zealthy |
|---|---|---|
| Monthly price | $199/mo | $99/mo |
| True annual cost | $2,388/yr | $1,188/yr |
| Labs included | ✗ No | ✗ No |
| Delivery options | injection | injection, oral |
| Editorial score | 8.8/10 | 8.3/10 |
| Trustpilot | 4.5★ | 4.4★ |
| State availability | All 50 states | All 50 states |
Our verdict
DirectMeds (8.8/10) is our pick over Zealthy (8.3/10) for most patients.
Zealthy may be a better fit if you want more delivery options (injection, oral). Both clinics require a prescription and blood work before starting treatment.
More GLP-1 / Weight Loss comparisons
DirectMeds vs Remedy Meds
$199/mo vs $179/mo · 8.8 vs 9.5 score
DirectMeds vs CareBare
$199/mo vs $199/mo · 8.8 vs 8.7 score
DirectMeds vs Enhance MD
$199/mo vs $115/mo · 8.8 vs 8.7 score
DirectMeds vs Strut Health
$199/mo vs $79/mo · 8.8 vs 8.6 score
Zealthy vs Remedy Meds
$99/mo vs $179/mo · 8.3 vs 9.5 score
Zealthy vs CareBare
$99/mo vs $199/mo · 8.3 vs 8.7 score