GLP-1 / Weight Loss › Head-to-head comparison
MEDVi vs DirectMeds
True annual cost, labs inclusion, delivery methods, and verified reviews compared. Updated March 2026.
★
Our pick: DirectMeds — 8.8/10 vs 8.5/10, $960/yr cheaper
MEDVi
$179/mo first month — top-rated GLP-1 provider
8.5/10
Monthly
$179/mo
True Annual
$3,348/yr
Labs
✗ Extra
States
All 50
Pros
✓Top-rated GLP-1 provider (100k+ patients)
✓Both sema and tirzepatide
✓LegitScript certified
Cons
✗Ongoing cost $299/mo is higher
✗No labs included
VS
★ Our Pick
DirectMeds
Compounded GLP-1 from $199/mo — semaglutide and tirzepatide, labs optional
8.8/10
Monthly
$199/mo
True Annual
$2,388/yr
Labs
✗ Extra
States
All 50
Pros
✓Fast approval process — under 24 hours
✓Compounded sema and tirzepatide available
✓Free shipping on all orders
Cons
✗Labs not included
✗Newer provider
Side-by-side comparison
| Feature | MEDVi | DirectMeds |
|---|---|---|
| Monthly price | $179/mo | $199/mo |
| True annual cost | $3,348/yr | $2,388/yr |
| Labs included | ✗ No | ✗ No |
| Delivery options | injection | injection |
| Editorial score | 8.5/10 | 8.8/10 |
| Trustpilot | 4.7★ | 4.5★ |
| State availability | All 50 states | All 50 states |
Our verdict
DirectMeds (8.8/10) is our pick over MEDVi (8.5/10) for most patients. At $2,388/yr vs $3,348/yr, DirectMeds saves you $960 per year.
MEDVi may be a better fit if you prefer MEDVi's specific protocol approach. Both clinics require a prescription and blood work before starting treatment.
More GLP-1 / Weight Loss comparisons
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DirectMeds vs Strut Health
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MEDVi vs Remedy Meds
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MEDVi vs CareBare
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