HRT › Head-to-head comparison
Sesame Care vs Winona
True annual cost, labs inclusion, delivery methods, and verified reviews compared. Updated March 2026.
★
Our pick: Sesame Care — 8.3/10 vs 8.1/10, $996/yr cheaper
★ Our Pick
Sesame Care
Direct-to-patient marketplace — GLP-1, ED, HRT, mental health from $16/appt
8.3/10
Monthly
$16/mo
True Annual
$192/yr
Labs
✗ Extra
States
All 50
Pros
✓Available in all 50 states
✓No insurance required — transparent cash pricing
✓Same-day telehealth or in-person appointments
Cons
✗Marketplace model — quality varies by provider
✗Lower recurring revenue than subscription clinics
VS
Winona
$99/mo — bioidentical HRT shipped to your door
8.1/10
Monthly
$99/mo
True Annual
$1,188/yr
Labs
✗ Extra
States
Most states
Pros
✓Bioidentical compounded hormones
✓No lab testing required
✓Fast onboarding
Cons
✗No labs included
✗Cream or pill only
Side-by-side comparison
| Feature | Sesame Care | Winona |
|---|---|---|
| Monthly price | $16/mo | $99/mo |
| True annual cost | $192/yr | $1,188/yr |
| Labs included | ✗ No | ✗ No |
| Delivery options | oral, injection, topical | cream, pill |
| Editorial score | 8.3/10 | 8.1/10 |
| Trustpilot | 4.5★ | 4.4★ |
| State availability | All 50 states | Most US states |
Our verdict
Sesame Care (8.3/10) is our pick over Winona (8.1/10) for most patients. At $192/yr vs $1,188/yr, Sesame Care saves you $996 per year.
Winona may be a better fit if you prefer Winona's specific protocol approach. Both clinics require a prescription and blood work before starting treatment.
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Sesame Care vs Evernow
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Winona vs Midi Health
$99/mo vs $0/mo · 8.1 vs 9.1 score
Winona vs Alloy
$99/mo vs $49/mo · 8.1 vs 8.4 score