HRT › Head-to-head comparison
Sesame Care vs Alloy
True annual cost, labs inclusion, delivery methods, and verified reviews compared. Updated March 2026.
★
Our pick: Alloy — 8.4/10 vs 8.3/10, higher rated
Sesame Care
Direct-to-patient marketplace — GLP-1, ED, HRT, mental health from $16/appt
8.3/10
Monthly
$16/mo
True Annual
$192/yr
Labs
✗ Extra
States
All 50
Pros
✓Available in all 50 states
✓No insurance required — transparent cash pricing
✓Same-day telehealth or in-person appointments
Cons
✗Marketplace model — quality varies by provider
✗Lower recurring revenue than subscription clinics
VS
★ Our Pick
Alloy
$49/mo — affordable HRT with strong women's community
8.4/10
Monthly
$49/mo
True Annual
$738/yr
Labs
✗ Extra
States
Most states
Pros
✓Lowest cash-pay price
✓Strong women's community
✓Multiple delivery options
Cons
✗Labs not included
Side-by-side comparison
| Feature | Sesame Care | Alloy |
|---|---|---|
| Monthly price | $16/mo | $49/mo |
| True annual cost | $192/yr | $738/yr |
| Labs included | ✗ No | ✗ No |
| Delivery options | oral, injection, topical | patch, cream, pill |
| Editorial score | 8.3/10 | 8.4/10 |
| Trustpilot | 4.5★ | 4.5★ |
| State availability | All 50 states | Most US states |
Our verdict
Alloy (8.4/10) is our pick over Sesame Care (8.3/10) for most patients.
Sesame Care may be a better fit if you prefer Sesame Care's specific protocol approach. Both clinics require a prescription and blood work before starting treatment.
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Sesame Care vs Midi Health
$16/mo vs $0/mo · 8.3 vs 9.1 score
Sesame Care vs Winona
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