GLP-1 / Weight Loss › Head-to-head comparison
Enhance MD vs Novi
True annual cost, labs inclusion, delivery methods, and verified reviews compared. Updated March 2026.
★
Our pick: Enhance MD — 8.7/10 vs 8.5/10, labs included
★ Our Pick
Enhance MD
GLP-1 & NAD+ from $115/mo — labs included, physician-led, all-inclusive pricing
8.7/10
Monthly
$115/mo
True Annual
$1,380/yr
Labs
✓ Included
States
Most states
Pros
✓Labs included in all plans — true all-in pricing
✓Physician-led with ongoing virtual care
✓NAD+, GLP-1, and GIP/GLP-1 (tirzepatide) all available
Cons
✗Not available in 11 states (AL, AR, GA, HI, LA, MS, MO, ND, SC, TN, WV)
✗GLP-1 focused — not a full mens health platform
VS
Novi
GLP-1 weight loss — $300 CPA | physician-supervised, compounded sema
8.5/10
Monthly
$179/mo
True Annual
$2,148/yr
Labs
✗ Extra
States
Most states
Pros
✓$300 CPA highest GLP-1 payout
✓Physician-supervised protocol
✓Compounded semaglutide
Cons
✗Newer provider
✗Limited public reviews
Side-by-side comparison
| Feature | Enhance MD | Novi |
|---|---|---|
| Monthly price | $115/mo | $179/mo |
| True annual cost | $1,380/yr | $2,148/yr |
| Labs included | ✓ Yes | ✗ No |
| Delivery options | injection | injection |
| Editorial score | 8.7/10 | 8.5/10 |
| Trustpilot | 4.4★ | 4.4★ |
| State availability | 38 US states (excl. AL, AR, GA, HI, LA, MS, MO, ND, SC, TN, WV) | Most US states |
Our verdict
Enhance MD (8.7/10) is our pick over Novi (8.5/10) for most patients. Labs are included in Enhance MD's monthly price — Novi charges separately, adding $150–300/yr to the true annual cost. At $1,380/yr vs $2,148/yr, Enhance MD saves you $768 per year.
Novi may be a better fit if you prefer Novi's specific protocol approach. Both clinics require a prescription and blood work before starting treatment.
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