GLP-1 / Weight Loss › Head-to-head comparison
DirectMeds vs Titan Medical
True annual cost, labs inclusion, delivery methods, and verified reviews compared. Updated March 2026.
★
Our pick: Titan Medical — 9.5/10 vs 8.8/10, $971/yr cheaper
DirectMeds
Compounded GLP-1 from $199/mo — semaglutide and tirzepatide, labs optional
8.8/10
Monthly
$199/mo
True Annual
$2,388/yr
Labs
✗ Extra
States
All 50
Pros
✓Fast approval process — under 24 hours
✓Compounded sema and tirzepatide available
✓Free shipping on all orders
Cons
✗Labs not included
✗Newer provider
VS
★ Our Pick
Titan Medical
Get started for $49 — editor's choice TRT
9.5/10
Monthly
$99/mo
True Annual
$1,417/yr
Labs
✗ Extra
States
Most states
Pros
✓Lowest starting cost ($49)
✓$100 off promo consistently available
✓All delivery methods
Cons
✗Ongoing price after promo varies
✗Not available in all states
Side-by-side comparison
| Feature | DirectMeds | Titan Medical |
|---|---|---|
| Monthly price | $199/mo | $99/mo |
| True annual cost | $2,388/yr | $1,417/yr |
| Labs included | ✗ No | ✗ No |
| Delivery options | injection | injection, oral, cream |
| Editorial score | 8.8/10 | 9.5/10 |
| Trustpilot | 4.5★ | 4.7★ |
| State availability | All 50 states | Most US states |
Our verdict
Titan Medical (9.5/10) is our pick over DirectMeds (8.8/10) for most patients. At $1,417/yr vs $2,388/yr, Titan Medical saves you $971 per year.
DirectMeds may be a better fit if you prefer DirectMeds's specific protocol approach. Both clinics require a prescription and blood work before starting treatment.
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