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GLP-1 / Weight Loss Head-to-head comparison

DirectMeds vs Maximus

True annual cost, labs inclusion, delivery methods, and verified reviews compared. Updated March 2026.

Our pick: Maximus9.4/10 vs 8.8/10, labs included
DirectMeds
Compounded GLP-1 from $199/mo — semaglutide and tirzepatide, labs optional
8.8/10
Monthly
$199/mo
True Annual
$2,388/yr
Labs
✗ Extra
States
All 50
Pros
Fast approval process — under 24 hours
Compounded sema and tirzepatide available
Free shipping on all orders
Cons
Labs not included
Newer provider
Visit DirectMeds
VS
★ Our Pick
Maximus
$99.99/mo annually — AI-powered protocols
9.4/10
Monthly
$100/mo
True Annual
$1,300/yr
Labs
✓ Included
States
All 50
Pros
Multiple delivery methods
Labs included
HCG available
Cons
Annual commitment for best price
Visit Maximus

Side-by-side comparison

FeatureDirectMedsMaximus
Monthly price$199/mo$100/mo
True annual cost$2,388/yr$1,300/yr
Labs included✗ No✓ Yes
Delivery optionsinjectioninjection, cream, oral
Editorial score8.8/109.4/10
Trustpilot4.5★4.6★
State availabilityAll 50 statesAll 50 states

Our verdict

Maximus (9.4/10) is our pick over DirectMeds (8.8/10) for most patients. Labs are included in Maximus's monthly price — DirectMeds charges separately, adding $150–300/yr to the true annual cost. At $1,300/yr vs $2,388/yr, Maximus saves you $1,088 per year.

DirectMeds may be a better fit if you prefer DirectMeds's specific protocol approach. Both clinics require a prescription and blood work before starting treatment.

Visit MaximusSee all GLP-1 / Weight Loss clinics →

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Maximus vs Enhance MD
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Maximus vs Strut Health
$100/mo vs $79/mo · 9.4 vs 8.6 score
DirectMeds vs Remedy Meds
$199/mo vs $179/mo · 8.8 vs 9.5 score
DirectMeds vs CareBare
$199/mo vs $199/mo · 8.8 vs 8.7 score
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